Bio-Activation of HA/β-TCP Porous Scaffolds by High-Pressure CO

Autor:	Clémentine, Aubry, Christophe, Drouet, Thierry, Azaïs, Hyoung-Jun, Kim, Jae-Min, Oh, Ipek, Karacan, Joshua, Chou, Besim, Ben-Nissan, Séverine, Camy, Sophie, Cazalbou
Rok vydání:	2022
Zdroj:	Materials (Basel, Switzerland). 15(20)
ISSN:	1996-1944
Popis:	Biphasic macroporous Hydroxyapatite/β-Tricalcium Phosphate (HA/β-TCP) scaffolds (BCPs) are widely used for bone repair. However, the high-temperature HA and β-TCP phases exhibit limited bioactivity (low solubility of HA, restricted surface area, low ion release). Strategies were developed to coat such BCPs with biomimetic apatite to enhance bioactivity. However, this can be associated with poor adhesion, and metastable solutions may prove difficult to handle at the industrial scale. Alternative strategies are thus desirable to generate a highly bioactive surface on commercial BCPs. In this work, we developed an innovative "coating from" approach for BCP surface remodeling via hydrothermal treatment under supercritical CO
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::f4316c5c83e7472808e77bdf2934b5a6 https://pubmed.ncbi.nlm.nih.gov/36295371 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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