Cinnamomum cassia essential oil and its major constituent cinnamaldehyde induced cell cycle arrest and apoptosis in human oral squamous cell carcinoma HSC-3 cells

Autor:	Wen-Lun, Chang, Fu-Chou, Cheng, Shu-Ping, Wang, Su-Tze, Chou, Ying, Shih
Rok vydání:	2015
Předmět:	Membrane Potential Mitochondrial Cell Survival Apoptosis Cell Cycle Checkpoints Antineoplastic Agents Phytogenic Cell Line Tumor Carcinoma Squamous Cell Oils Volatile Humans Mouth Neoplasms Acrolein Reactive Oxygen Species Cinnamomum DNA Damage
Zdroj:	Environmental toxicology. 32(2)
ISSN:	1522-7278
Popis:	Cinnamomum cassia essential oil (CC-EO) has various functional properties, such as anti-microbial, hypouricemic, anti-tyrosinase and anti-melanogenesis activities. The present study aimed to evaluate the anti-cancer activities of CC-EO and its major constituent, cinnamaldehyde, in human oral squamous cell carcinoma HSC-3 cells. Determination of the cell viability, apoptotic characteristics, DNA damage, cell cycle analysis, reactive oxygen species (ROS) production, mitochondrial membrane potential, cytosolic Ca
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::f41c1ba6dadd34d73992b9437c667d57 https://pubmed.ncbi.nlm.nih.gov/26919256 Zobrazit plný text záznamu Plný text