[Pathological Complete Response in Multiple Advanced Rectal Cancers with Neoadjuvant CapeOX plus BV Therapy-A Case Report]

Autor: Komei, Kuge, Akihisa, Matsuda, Takeaki, Fujihira, Yasuo, Baba, Takeshi, Yamada, Satoshi, Matsumoto, Hideyuki, Suzuki, Norio, Fujihira, Hiroshi, Yoshida
Rok vydání: 2020
Předmět:
Zdroj: Gan to kagaku ryoho. Cancerchemotherapy. 47(9)
ISSN: 0385-0684
Popis: A 70-year-old male with defecation difficulties was referred to our hospital. A colonoscopy and computed tomography revealed multiple advanced rectal cancers in the rectosigmoid and lower rectum with swollen lymph nodes. After 6 courses of neoadjuvant capecitabine and oxaliplatin and bevacizumab without radiotherapy(CapeOX plus BV therapy), a colonoscopy revealed that the tumors had significantly reduced. A low anterior laparoscopic resection with diverting ileostomy was performed. Histopathological examination showed no residual tumor cells or lymph node metastasis. A final diagnosis of pathological complete response was made. The patient has currently survived 1-year disease-free. Neoadjuvant CapeOX plus BV therapy can be a promising therapeutic option for locally advanced rectal cancer.
Databáze: OpenAIRE