Differential gene expression after implantation of biomaterials into rat gastrointestine

Autor: M, Löbler, M, Sass, P, Michel, U T, Hopt, C, Kunze, K P, Schmitz
Rok vydání: 2004
Zdroj: Journal of materials science. Materials in medicine. 10(12)
ISSN: 0957-4530
Popis: Two biodegradable materials, polyglycolide-copoly(L)-lactide/poly-dioxanone composite and poly(3-hydroxybutyrate), have been employed for surgery in the gastrointestine of laboratory rats. The tissue response was analyzed at distinct time intervals up to 2 months by differential mRNA display. Two specific PCR fragments were transiently present 7 and 14 days after contact with poly(3-hydroxybutyrate). Both fragments represent distinct rat lipases which might play a role in poly(3-hydroxybutyrate) degradation.
Databáze: OpenAIRE