Substrate specificity and energetics of antiseptic and disinfectant resistance in Staphylococcus aureus

Autor:	T G, Littlejohn, I T, Paulsen, M T, Gillespie, J M, Tennent, M, Midgley, I G, Jones, A S, Purewal, R A, Skurray
Rok vydání:	1992
Předmět:	Staphylococcus aureus Phenotype Genes Bacterial Ethidium Anti-Infective Agents Local Biological Transport Active Humans Drug Resistance Microbial Disinfectants Substrate Specificity
Zdroj:	FEMS microbiology letters. 74(2-3)
ISSN:	0378-1097
Popis:	Clinical isolates of Staphylococcus aureus carry various antiseptic and disinfectant resistance determinants (qac genes) on a variety of plasmids. The biochemistry and specificity of these resistance genes in S. aureus is the subject of this report. The qac genes were separated into two families on the basis of resistance profiles and DNA homology. Isotopic and fluorimetric assays demonstrated that the qac genes encode efflux systems that rely on proton motive force.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::f38f66d9dadbb764b090d1edc84165f5 https://pubmed.ncbi.nlm.nih.gov/1526458 Zobrazit plný text záznamu Plný text