Benefits and Challenges of the Use of Two Novel vB_Efa29212_2e and vB_Efa29212_3e Bacteriophages in Biocontrol of the Root Canal

Autor:	Magdalena, Moryl, Aleksandra, Palatyńska-Ulatowska, Agnieszka, Maszewska, Iwona, Grzejdziak, Silvia, Dias de Oliveira, Marieli Chitolina, Pradebon, Liviu, Steier, Antoni, Różalski, Jose Antonio, Poli de Figueiredo
Rok vydání:	2022
Zdroj:	Journal of clinical medicine. 11(21)
ISSN:	2077-0383
Popis:	Bacteriophage therapy has emerged as a strategy supplementing traditional disinfection protocols to fight biofilms. The aim of the study was to isolate the phages againstIsolated phages differed in morphology. Taxonomy for vB_Efa29212_2e (Siphoviridae, Efquatovirus) and for vB_Efa29212_3e (Herelleviridae, Kochikohdavirus) was confirmed. Both phages were stable at a temperature range of 4-50 °C and showed a different tolerance to chemicals: 15% EDTA, 1-3% sodium hypochlorite, and chlorhexidine. SEM analysis showed distortion of bacteria cells after phage inoculation, which proved the lytic activity againstResults strongly support the concept that phage therapy has a real therapeutic potential for the prevention and treatment of
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::f389c1a5aa098a83865f9a0fae1208cf https://pubmed.ncbi.nlm.nih.gov/36362722 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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