[Molecular aspects of the mechanism of anti-oxidant activity of vitamin E: features of the action of alpha- and gamma-tocopherol]

Autor: B B, Aĭdarkhanov, E A, Lokshina, E G, Lenskaia
Rok vydání: 1989
Předmět:
Zdroj: Voprosy meditsinskoi khimii. 35(3)
ISSN: 0042-8809
Popis: Current data on mechanisms of vitamin E action are reviewed with the specific reference to the antioxidant theory. Experimental data relevant to this theory on alpha- and gamma-tocopherols reactions in biological and nonbiological systems are considered. Distinctly lower biological activity of gamma-tocopherol, as compared with that of alpha-tocopherol, was shown not to depend only on dissimilar antiradical properties of these two homologues. Tocopherol-binding proteins, exhibiting high affinity only to alpha-tocopherol, appear to be responsible for realization of the biologically important reactions.
Databáze: OpenAIRE