| Autor: |
I V, Smirnov, T O, Murashko, A A, Ivanov, A O, Nemtsev, A A, Bondarev, V V, Udut |
| Rok vydání: |
2016 |
| Předmět: |
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| Zdroj: |
Eksperimental'naia i klinicheskaia farmakologiia. 78(12) |
| ISSN: |
0869-2092 |
| Popis: |
This study was aimed at estimation of the diuretic and saluretic activity of 4-nitrophenyl-O-β-D-glucopyranoside and its aglicon 4-nitrophenol in rats. Test animals daily received 4-nitrophenyl-O-β-D-glucopyranoside (group 1) and 4-nitrophenol (group 2) intragastrically in 2 mL of distilled water in a dose of 18 µmol/kg from 1st to 7th day and 54 µmol/kg from 8th to 14th days. During the experiment, the most pronounced diuretic activity was observed for 4-nitrophenyl-O-β-D-glucopyranoside in a dose of 54 µmol/kg, which increased the diuresis in rats 2.5 times as compared to the control value. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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