| Autor: |
F, Rondelli, S, Trastulli, R, Cirocchi, N, Avenia, E, Mariani, F, Sciannameo, G, Noya |
| Rok vydání: |
2011 |
| Předmět: |
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| Zdroj: |
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland. 14(11) |
| ISSN: |
1463-1318 |
| Popis: |
The effectiveness of rectal washout was compared with no washout for the prevention of local recurrence after anterior rectal resection for rectal cancer.The following electronic databases were searched: PubMed, OVID Medline, Cochrane Database of Systematic Reviews, EBM Reviews, CINAHL and EMBASE.Five nonrandomized studies including a total of 5012 patients were identified. Meta-analysis suggested that rectal washout significantly reduced the local recurrence rate (P0.0001; OR 0.57; 95% CI 0.43-0.74). It was also significantly lower after washout in patients having radical resection only (P = 0.0004; OR 0.54; 95% CI 0.39-0.76), patients treated by a curative resection (P0.0001; OR 0.55; 95% CI 0.42-0.72) and those undergoing preoperative radiotherapy (P = 0.04; OR 0.62; 95% CI 0.39-0.98).Taking into account the limitations of the design of the included studies the meta-analysis showed that rectal washout is associated with reduced local recurrence and therefore should be routine during anterior resection for rectal cancer. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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