[Use of recombinant human erythropoietin preparations as a blood-saving method in neurosurgery]

Autor: V V, Gromova, A A, Imaev, A Iu, Lubnin
Rok vydání: 2010
Předmět:
Zdroj: Anesteziologiia i reanimatologiia. (4)
ISSN: 0201-7563
Popis: The paper gives the results of the first clinical use of recombinant human erythropoietin (rhEPO) within the blood-saving program in neurosurgical patients with preoperative anemia of various genesis and predictable massive intraoperative blood loss. A course of effective therapy with rhEPO is shown to increase hemoglobin and packed cell volume rather rapidly in all patients prior to surgery. This made it possible to effectively apply other blood-saving procedures (isovolemic hemodilution and instrumental reinfusion of washed red blood cells) and to reduce the volume required for the use of donor transfused media in these patients. Various clinical aspects of the use of rhEPO in these patients are discussed.
Databáze: OpenAIRE