| Autor: |
J M, Alamo, A, Galindo, S, Morales, G, Daza, M, Socas, G, Suárez-Artacho, J M, Suárez-Grau, J, García-Moreno, F, Pareja, M A, Gómez |
| Rok vydání: |
2007 |
| Předmět: |
|
| Zdroj: |
Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva. 99(2) |
| ISSN: |
1130-0108 |
| Popis: |
some clinical, anatomo-pathological, and technical factors influence the correct healing of intestinal suture following an intestinal resection. One of the most influential factors is patient nutritional status.to evaluate the influence of malnutrition on the viability of primary intestinal anastomosis by the analysis of collagen I deposition.40 Wistar rats, radioimmunoassay material. We used 2 groups of rats, 20 animals in each group: a control group (A) and a "malnutrition" group (B).there was a decrease in PINP (procollagen) deposition in the colon of group B rats as compared to the colon of group A (0.3620 and 0.4340 mg/g respectively) (p = 0.032). There is an increase in ICTP (carboxyterminal telopeptide) in the colon of group B (0.9545 as against 0.8460 mg/g in group A) (p = 0.875). In anastomoses of group B there was a decrease in PINP synthesis as compared to group A (0.376 and 0.468 mg/g respectively, p = 0.002). As regards ICTP, there was an increase in group B (p = 0.330). In relation to the control group no differences were observed in ICTP increases in group B (p = 1).colonic anastomosis increases the levels of PINP and ICTP in healed tissue (p = 0.000); malnutrition reduces collagenization in anastomoses (p = 0.000). |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
