Autor: |
F, Antillon, F G, Behm, S C, Raimondi, S C, Kaste, J T, Sandlund, A S, Pappo |
Rok vydání: |
1998 |
Předmět: |
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Zdroj: |
Journal of pediatric hematology/oncology. 20(6) |
ISSN: |
1077-4114 |
Popis: |
A child with a primary lymphoma of bone (PLB) with a t(3;22)(q27;q11) is described.An 11-year-old boy had a 5-week history of back pain and a destructive lesion of S1 that contained an epidural component. Histologic evaluation of a biopsy confirmed the diagnosis of diffuse large B-cell non-Hodgkin lymphoma. Karyotypic analysis disclosed a t(3;22)(q27;q11), but the amount of tumor tissue was insufficient for molecular studies of the BCL-6 gene.The patient remains free of disease 4 years after completion of intensive systemic chemotherapy and intrathecal chemotherapy.The lymphoma in the patient described in this report is highly unusual because of the coexistence of pediatric PLB and a t(3;22)(q27q11). |
Databáze: |
OpenAIRE |
Externí odkaz: |
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