Statistical methods for studying multiple primary malignant neoplasms

Autor:	B S, Schoenberg, M H, Myers
Rok vydání:	1977
Předmět:	Adult Male Neoplasms Multiple Primary Risk Time Factors Statistics as Topic Humans Female Registries Middle Aged Epidemiologic Methods United States Aged
Zdroj:	Cancer. 40
ISSN:	0008-543X
Popis:	Case reports and case series dealing with multiple primary malignant neoplasms provided useful criteria for defining and documenting this phenomenon. The formation of tumor registries greatly aided in identifying a sufficient number of multiple primary cancer patients and facilitated case-control comparisons. Reports of two or more neoplasms occurring together in the same individual do not constitute proof of a significant association; the tumors must be shown to occur together more frequently than expected by chance. The person-years approach applied to data derived from a well-defined population makes it possible to compare the observed and expected number of subsequent primary cancers. The results of the most sophisticated procedures are no better than the quality of the data, however, and one must critically examine possible sources of bias before accepting statistical significance as representing biologic significance.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::f2757f8097dc187946a1fab95eb36f59 https://pubmed.ncbi.nlm.nih.gov/907991 Zobrazit plný text záznamu Plný text