[Effect of a new prostaglandin aroxaprostol on the contractile activity of the uterus and its abortive action in experimental studies]

Autor:	V V, Korkhov, M N, Mats, N P, Pankrashkina, M G, Stepanov, V L, Khristoforov
Rok vydání:	1992
Předmět:	Time Factors Abortifacient Agents Action Potentials Abortion Induced Injections Intramuscular Models Biological Stimulation Chemical Rats Uterine Contraction Pregnancy Injections Intravenous Prostaglandins F Synthetic Prostaglandins Animals Female
Zdroj:	Akusherstvo i ginekologiia. (3-7)
ISSN:	0300-9092
Popis:	Experiments with pregnant and nonpregnant rats have shown that aroxaprostol, a group F2 alpha prostaglandin, injected intravenously and intramuscularly in a dose of 50 micrograms/kg, stimulates the uterine bioelectric activity, increasing both the amplitude and frequency of biopotentials, this evidencing intensification of its contractility. Aroxaprostol has shown an abortive effect, that was related to the luteolytic effect of the drug, manifesting by reduction of progesterone level in the ovaries.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::f17c976466479edc78cfe6b3dd8574cd https://pubmed.ncbi.nlm.nih.gov/1481958 Zobrazit plný text záznamu