Prophylactic total thyroidectomy using the minimally invasive video-assisted approach in children with multiple endocrine neoplasia type 2
| Autor: | Ronan W, Glynn, Emma C, Cashman, Jaime, Doody, Eimear, Phelan, John D, Russell, Conrad, Timon |
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| Rok vydání: | 2012 |
| Předmět: |
Male
Hematoma Operative Time Proto-Oncogene Proteins c-ret Multiple Endocrine Neoplasia Type 2a Video-Assisted Surgery United States Treatment Outcome Risk Factors Child Preschool Mutation Thyroidectomy Humans Female Genetic Predisposition to Disease Thyroid Neoplasms Child Codon Biomarkers Follow-Up Studies Retrospective Studies |
| Zdroj: | Headneck. 36(6) |
| ISSN: | 1097-0347 |
| Popis: | There have been few reports of prophylactic thyroidectomy using the minimally invasive video-assisted thyroidectomy (MIVAT) approach in children with multiple endocrine neoplasia 2 (MEN2).We conducted a retrospective review of a prospectively maintained database of patients who underwent MIVAT for total thyroidectomy.Six children underwent MIVAT; RET codon mutations identified were 634, 620, 611, and 918. Mean operative time was 93 minutes (range, 68-105 minutes). Five patients were discharged on the first postoperative day; however, 1 patient had a postoperative hematoma and was discharged 2 days postoperatively. There were no cases of laryngeal nerve palsy or postoperative hypoparathyroidism. High levels of satisfaction with postoperative cosmesis were reported. Calcitonin levels have been undetectable at follow-up thus far (mean follow-up, 42.8 months).Although our outcomes are similar to those reported using the traditional approach, it is important to note that MIVAT is essentially the same operation, just performed through a smaller incision, with resulting benefits in terms of pain, cosmesis and, perhaps, morbidity. |
| Databáze: | OpenAIRE |
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