[Clinical use of statins and cholesterol goals in patients with several cardiovascular risk factors]

Autor: Ana, Gómez-Belda, Enrique, Rodilla, Amparo, Albert, Luis, García, Carmen, González, José M, Pascual
Rok vydání: 2003
Předmět:
Zdroj: Medicina clinica. 121(14)
ISSN: 0025-7753
Popis: Our goal was to determine the number of patients who achieve low-density lipoprotein cholesterol (LDL-c) targets according to new guidelines.Descriptive and transversal study of patients from a cardiovascular clinic. LDL-c was calculated and targets were established according the NCEP-ATP III.1,811 patients (46% males, 54% females) were studied. 35% of these were high-risk patients (group 1: coronary risk20% at 10 years), 19% were intermediate-risk patients (group 2: coronary risk 10-20% at 10 years) and 46% were low-risk patients (group 3: coronary risk10% at 10 years). Overall, 58% of patients achieved target LDL-c levels, yet success rates were 26% among group 1 patients, 51% among group 2 patients, and 86% among group 3 patients (p = 0.001, for differences between groups). Statin treatment was significantly related to achieving target LDL-c levels in group 1 patients (OR = 1.7; 95% CI, 1.2-2.4; p = 0.007). In group 1.41% of patients had LDL-c levels130 mg/dl without receiving lipid-lowering drugs.Although an overall 58% patients achieve target LDL-C levels, only one of four high-risk patients have LDL-c levels100 mg/dl, and statin treatment is a determining factor to achieve this goal. These findings indicate that a more aggressive treatment with statins is needed in secondary prevention.
Databáze: OpenAIRE
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