Ctf4-related protein recruits LHP1-PRC2 to maintain H3K27me3 levels in dividing cells in

Autor: Yue, Zhou, Emmanuel, Tergemina, Haitao, Cui, Alexander, Förderer, Benjamin, Hartwig, Geo, Velikkakam James, Korbinian, Schneeberger, Franziska, Turck
Rok vydání: 2017
Předmět:
Zdroj: Proceedings of the National Academy of Sciences of the United States of America. 114(18)
ISSN: 1091-6490
Popis: Polycomb Repressive Complex (PRC) 2 catalyzes the H3K27me3 modification that warrants inheritance of a repressive chromatin structure during cell division, thereby assuring stable target gene repression in differentiated cells. It is still under investigation how H3K27me3 is passed on from maternal to filial strands during DNA replication; however, cell division can reinforce H3K27me3 coverage at target regions. To identify novel factors involved in the Polycomb pathway in plants, we performed a forward genetic screen for enhancers of the
Databáze: OpenAIRE