[Possible use of erythrocyte antioxidant enzymes as markers of the course of disease in patients with hemoblastoses]

Autor: A O, Kumerova, V I, Petukhov, A P, Shkesters, A A, Silova, A G, Letse
Rok vydání: 1996
Předmět:
Zdroj: Voprosy meditsinskoi khimii. 42(2)
ISSN: 0042-8809
Popis: Blood and erythrocytes of 50 healthy volunteers and 105 patients with different forms of hemoblastoses were investigated. 54 patients had acute phase, 51 patients--remission stage of disease. Essential differences in the activity of antioxidant enzymes (SOD, CAT, GSH-Px) were detected and compared with content of MDA and degree of anaemia. Acute phase had more significantly alteration of antioxidant defence: diverse changes of the activity of SOD and CAT, significantly inhibition of GSH-Px, the high level of MDA and increased degree of anaemia.
Databáze: OpenAIRE