| Autor: |
Huawei, Li, Jufu, Wu, Zhongwen, Zhang, Yuanyuan, Ma, Fangfang, Liao, Yu, Zhang, Guojuan, Wu |
| Rok vydání: |
2010 |
| Předmět: |
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| Zdroj: |
Phytotherapy Research |
| ISSN: |
1099-1573 |
| Popis: |
Forsythoside A is a polyphenolic constituent of the fruits of Forsythia suspensa Vahl. which is widely used as an antiinflammatory agent in traditional Chinese medicine. In the present study, the effects of forsythoside A on cell infection by avian infectious bronchitis virus were assessed. A real‐time fluorescence quantitative PCR assay was used to determine mRNA content of IBV N gene. The pretreatment of cells with forsythoside A, adding forsythoside A post infection of cells, and treatment of virus with forsythoside A were analysed. The inhibitory effect of forsythoside A was confirmed by infecting primary chicken embryo kidney cells. Infected cells were inhibited by forsythoside A treatment. The data indicated that forsythoside A has the potential to prevent IBV infection in vitro. Copyright © 2010 John Wiley & Sons, Ltd. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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