Malignant histiocytosis presenting with vasculitis and cutaneous erythrophagocytosis

Autor: W W, Reed, J W, Patterson, F G, Behm, B, Littman, A, Garrett
Rok vydání: 1986
Předmět:
Zdroj: Cutis. 38(1)
ISSN: 0011-4162
Popis: We report a case of malignant histiocytosis that presented initially as a cutaneous vasculitis without malignant features. A subsequent biopsy specimen of an erythematous skin lesion showed erythrophagocytosis by normal-appearing histiocytes within the subcutis. The recognition of erythrophagocytosis was followed by systemic symptoms and signs of malignant histiocytosis and a rapidly deteriorating clinical course. Possible mechanisms for erythrophagocytosis are discussed, and other diseases associated with this histologic finding are reviewed briefly.
Databáze: OpenAIRE