| Autor: |
Yoko, Mamada, Takahiro, Murata, Ayumi, Taniguchi, Yuki, Hasegawa, Tetsuomi, Suzuki, Kyoko, Kohda, Kiyoto, Nasuno, Toshiaki, Watanabe, Seiji, Yamaguchi, Akira, Ishiguro |
| Rok vydání: |
2007 |
| Předmět: |
|
| Zdroj: |
Arerugi = [Allergy]. 57(5) |
| ISSN: |
0021-4884 |
| Popis: |
We reported a 4-month-old girl with biotin deficiency caused by amino acid formula. Two weeks after birth, she was diagnosed as having a milk protein allergy. After switching to amino acid formula from usual formula, her symptoms and laboratory findings became normal. About three weeks after the beginning of amino acid formula, she developed intractable skin erosions around the eyes, mouth, neck, and anogenital area. By measuring concentrations of some trace elements, she was diagnosed as having a biotin deficit, because of the organic aciduria and undetectable serum biotin concentration. Her serum biotinidase level was normal. Upon administration of oral biotin supplementation, all her symptoms and laboratory findings were dramatically improved. Since amino acid formula contains very few biotin, we should pay attention to biotin deficiency when infants receiving amino acid formula. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
