Hyperlipidemic acute pancreatitis: a possible role of antiretroviral therapy with entecavir
| Autor: | A, Durval, L, Zamidei, D, Bettocchi, M G, Luzzio, G, Consales |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Adult
Hypertriglyceridemia Male Guanine Critical Care Fever Adenine Organophosphonates Hyperlipidemias Plasmapheresis Abdominal Pain Alcoholism Hepatitis B Chronic Diabetes Mellitus Type 2 Pancreatitis Antiretroviral Therapy Highly Active Acute Disease Humans Reverse Transcriptase Inhibitors Tenofovir Tomography X-Ray Computed Triglycerides |
| Zdroj: | Minerva anestesiologica. 77(10) |
| ISSN: | 1827-1596 |
| Popis: | In most cases clinical profile of acute hyperlipidemic pancreatitis is a preexisting lipoprotein abnormality associated to second risk factors such as alcohol abuse, diabetes mellitus or medications that can induce hypertrygliceridemia. We report a case of a young male affected by chronic hepatitis B virus infection admitted to Emergency Department due to acute abdominal pain, vomiting and fever. The patient was in antiretroviral treatment with entecavir; moreover he was affected by diabetes mellitus and he presented a past history of alcohol abuse. Laboratory tests demonstrated hyperglycemia, severe metabolic acidosis and hypertriglyceridemia, whereas abdominal computed tomography scan revealed peripancreatic edema: hyperlipidemic pancreatitits was supposed and the patient was admitted to the intensive care unit. Considering its possible role in the pathogenesis of pancreatitis, entecavir was interrupted and total of 3 sections of plasmapheresis were performed, allowing clinical resolution and prevention of pancreatic damage. The possible pathogenetic role of entecavir is discussed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|