Epigenetic reprogramming in the mammalian embryo: struggle of the clones

Autor: Mann, Mellissa RW, Bartolomei, Marisa S
Jazyk: angličtina
Rok vydání: 2002
Předmět:
Zdroj: Genome Biology
ISSN: 1465-6914
1465-6906
Popis: During preimplantation development in mammals, distinct epigenetic marks on oocyte and sperm DNA are remodeled to an embryonic pattern. A recent study examining global methylation of repetitive elements in various mammals showed that the reprogramming that occurs during normal preimplantation development is aberrant in cloned embryos.
Databáze: OpenAIRE