Epigenetic reprogramming in the mammalian embryo: struggle of the clones
Autor: | Mann, Mellissa RW, Bartolomei, Marisa S |
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Jazyk: | angličtina |
Rok vydání: | 2002 |
Předmět: | |
Zdroj: | Genome Biology |
ISSN: | 1465-6914 1465-6906 |
Popis: | During preimplantation development in mammals, distinct epigenetic marks on oocyte and sperm DNA are remodeled to an embryonic pattern. A recent study examining global methylation of repetitive elements in various mammals showed that the reprogramming that occurs during normal preimplantation development is aberrant in cloned embryos. |
Databáze: | OpenAIRE |
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