| Autor: |
Chiang, Gloria C., Mao, Xiangling, Kang, Guoxin, Chang, Eileen, Pandya, Sneha, Vallabhajosula, Shankar, Isaacson, Richard, Ravdin, Lisa D., Shungu, Dikoma C. |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
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| Popis: |
Oxidative stress has been implicated as an important pathologic mechanism in the development of Alzheimer disease. The purpose of this study was to assess whether glutathione levels, detected noninvasively with proton MR spectroscopy, are associated with brain amyloidosis and memory in a community-dwelling cohort of healthy older adults.Fifteen cognitively healthy subjects were prospectively enrolled in this study. All subjects underwentLower glutathione levels were associated with greater brain amyloidosis in the temporal (This study found an association between cortical glutathione levels and brain amyloidosis in healthy older adults, suggesting a potential role for |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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