| Autor: |
Duo-Xi, Deng, Jie, Tan, Hong, Zhang, Gui-Lan, Huang, Shuai, Li, Kui-Kui, Guo, Yun-Yun, Wu, Bi-Ying, Yang, Yao, Xiao, Liang, Peng, Hui, Xie |
| Rok vydání: |
2018 |
| Předmět: |
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| Zdroj: |
Zhen ci yan jiu = Acupuncture research. 43(8) |
| ISSN: |
1000-0607 |
| Popis: |
To observe the effect of electroacupuncture (EA) stimulation of "Shangjuxu" (ST 37, Lower Confluent point) and "Tianshu" (ST 25, Front-Mu point) on visceral pain and expression of colonic tryptase(Try), proteinase-activated receptor 2(PAR-2)，transient receptor potential channel vanilloid subfamily member 1 (TPRV 1)，substance P (SP) and calcitonin gene-related peptide (CGRP) in rats with irritable bowel syndrome (IBS), so as to explore its mechanisms underlying improvement of IBS.Forty male Sprague Dawley rats were equally randomized into normal control (control), model, medication and EA groups (After modeling, the body weight was significantly decreased in IBS rats of the model, medication and EA groups compared with their own individual pre-treatment and with the control group (EA of ST 37 and ST 25 can relieve visceral hypersensitivity in IBS rats, which may be associated with its effects in down-regulating the number of MC and the expression of PAR-2, TRVP 1, SP, CGRP and Try proteins in the colonic tissue. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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