Ip immunotherapy and chemotherapy in advanced epithelial ovarian cancer

Autor: E, Hernandez, N B, Rosenshein, J, Pino y Torres, J, Villar, F C, Grumbine, D S, Ettinger, M B, Dillon, J L, Klein, S E, Order
Rok vydání: 1982
Předmět:
Zdroj: Cancer treatment reports. 66(11)
ISSN: 0361-5960
Popis: Nine patients with advanced epithelial ovarian cancer, classified as either stage III with macrometastatic residual disease or stage IV, received combination chemotherapy in conjunction with ip rabbit-derived human ovarian antitumor serum (HOATS). The HOATS regimen consisted of the ip instillation of 100 ml of ovarian antitumor serum on Days 1 and 3 of the first chemotherapy cycle. Side effects attributable to HOATS were low-grade fever in three patients and diffuse skin rash in two. The 1-year cumulative survival was 87%, with a clinical response rate of 80%. No significant toxic reactions to HOATS have been observed. Continuation of the present study seems justified.
Databáze: OpenAIRE