| Autor: |
Davies, N., Moir, G., Carpenter, R., Cuthbert, A., Herbert, A., Royle, G. T., Taylor, I. |
| Jazyk: |
angličtina |
| Rok vydání: |
1991 |
| Předmět: |
|
| Popis: |
Oestrogen receptor status has been determined by an immunocytochemical assay using fine-needle aspiration samples of primary breast cancers in elderly patients. In a prospective study 56 patients were treated with tamoxifen only. Satisfactory assays were achieved in 49 patients. Disease was controlled by tamoxifen in 32 of 35 (91%) patients with oestrogen receptor positive tumours, compared with only 1 (7%) of 14 who were receptor negative. Immunocytochemical assay on fine-needle aspiration samples is relatively non-invasive and simple to perform, it accurately predicts response to tamoxifen in elderly patients and can be used to select patients for tamoxifen only therapy. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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