Quinidine syncope. A report of successful treatment with bretylium tosylate

Autor: C R, VanderArk, E W, Reynolds, D R, Kahn, G, Tullett
Rok vydání: 1976
Předmět:
Zdroj: The Journal of thoracic and cardiovascular surgery. 72(3)
ISSN: 0022-5223
Popis: Quinidine syncope is an unpredictable side effect of quinidine administrateion which has a mortality rate of 11.5 per cent when managed with conventional drugs and direct-current countershock. In 2 patients with quindine syncope, the arrhythmias were effectively controlled within 30 minutes following the slow infusion of 150 mg. of bretylium tosylate. This control is contrasted with 2 cases managed in the conventional manner. Bretylium tosylate is a quaternary amine with unique antifibrillatory properties and appears to have a significant role in the management of these arrhylmias.
Databáze: OpenAIRE