| Popis: |
To compare the prevalence of risk factors, and the response to pravastatin treatment between men and women.We evaluated 486 men and 386 women, of these 230 men and 187 women received 10 mg of pravastatin for three months.There were differences between women and men in respectively: arterial hypertension (45.5% vs 40.8%; p = 0.0012), left ventricular hypertrophy (33.0% vs 22.0%; p = 0.0041), sedentarism (94.8% vs 87.8%; p = 0.0005), smoking (43.0% vs 61.8%; p0.0001), Framingham scores (20.0 +/- 7.1 vs 16.0 +/- 7.6 p0.0001), HDL-C (43.0 +/- 11.0 vs 38.0 +/- 9.0 mg/dL; p 0.001), triglycerides-TG (216.0 +/- 115.0 vs 271.0 +/- 172.0 mg/dL; p0.001) and Castelli's indexes (CI) I and II (7.7 +/- 2.6 vs 8.6 +/- 3.2; p = 0.002 and 5.0 +/- 1.5 vs 5.5 +/- 2.0; p = 0.015). In men under pravastatin treatment there was a greater reduction in TG (32.0 vs 21.0% p0.05) and CI I (-41.0% vs -37.0%; p0.05) and II (-40.0% vs -38.0%; p0.05).Men and women differed in risk factors prevalence and response to treatment with pravastatin. |
