Acute tumor lysis syndrome with choriocarcinoma

Autor:	C D, Blanke, M P, Hemmer, R S, Witte
Rok vydání:	2000
Předmět:	Male Antibiotics Antineoplastic Lung Neoplasms Hypocalcemia Liver Neoplasms Antineoplastic Agents Middle Aged Antineoplastic Agents Phytogenic Heart Arrest Phosphates Uric Acid Bleomycin Fatal Outcome Testicular Neoplasms Lymphatic Metastasis Acute Disease Antineoplastic Combined Chemotherapy Protocols Humans Hyperkalemia Choriocarcinoma Cisplatin Acidosis Respiratory Insufficiency Tumor Lysis Syndrome Etoposide
Zdroj:	Southern medical journal. 93(9)
ISSN:	0038-4348
Popis:	A 52-year-old man with retroperitoneal nodal, lung, and liver metastases from choriocarcinoma received chemotherapy with etoposide, cisplatin, and bleomycin. Within 48 hours of starting treatment, he had hypotension, hypoxemia, and anuria. Laboratory values showed hyperuricemia, hyperkalemia, hyperphosphatemia, hypocalcemia, and metabolic acidosis. He was placed on mechanical ventilation, and hemodialysis was instituted, with marked improvement in renal function. A second, shortened course of chemotherapy with carboplatin and etoposide was given 21 days later. However, on hospital day 48, the patient died of progressive pulmonary insufficiency and cardiac arrest. This represents the first reported case of acute tumor lysis syndrome after systemic chemotherapy for advanced nonseminomatous germ cell cancer.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::eebfe6f77f2e9cc5af25ea4fea534b60 https://pubmed.ncbi.nlm.nih.gov/11005356 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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