The structure of the core region of the lipopolysaccharide from Klebsiella pneumoniae O3. 3-deoxy-alpha-D-manno-octulosonic acid (alpha-Kdo) residue in the outer part of the core, a common structural element of Klebsiella pneumoniae O1, O2, O3, O4, O5, O8, and O12 lipopolysaccharides

Autor:	E, Vinogradov, M, Cedzynski, A, Ziolkowski, A, Swierzko
Rok vydání:	2001
Předmět:	Lipopolysaccharides Klebsiella pneumoniae Magnetic Resonance Spectroscopy Carbohydrate Sequence Molecular Sequence Data Sugar Acids Gas Chromatography-Mass Spectrometry
Zdroj:	European journal of biochemistry. 268(6)
ISSN:	0014-2956
Popis:	The structure of lipid A-core region of the lipopolysaccharide (LPS) from Klebsiella pneumoniae serotype O3 was determined using NMR, MS and chemical analysis of the oligosaccharides, obtained by mild acid hydrolysis, alkaline deacylation, and deamination of the LPS: [carbohydrate structure see text] where P is H or alpha-Hep; J is H or beta-GalA; R is H or P (in the deacylated oligosaccharides). Screening of the LPS from K. pneumoniae O1, O2, O4, O5, O8, and O12 using deamination showed that they also contain alpha-Hep-(1--4)-alpha-Kdo-(2--6)-GlcN and alpha-Kdo-(2--6)-GlcN fragments.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::ee60f8dbd4e662729fa3774fb6fa8ee7 https://pubmed.ncbi.nlm.nih.gov/11248692 Zobrazit plný text záznamu Plný text