HIV-1 seroepidemiological profile in age groups and sexes in Benin City, Nigeria

Autor: N O, Eghafona, M N, Phillips, N, Uraih
Rok vydání: 1993
Předmět:
Zdroj: Tropical and geographical medicine. 45(6)
ISSN: 0041-3232
Popis: A pilot survey of 2,206 collected sera were screened for HIV-Ab by ELISA in the age groups 10-60 years. The age group 20-29 years recorded the highest HIV-1 Ab with 9/239 (3.77%). The age group 10-19, 30-39 and 40-49 recorded 3/192 (1.56%); 4/725 (0.55%) and 2/671 (0.3%), respectively. The age group50 years had 1/379 (0.26%). The relative rate was 3.29 between females and male with 95% confidence intervals of 1.33-8.14, p = 0.0125 by Fisher's Exact test. Conditioned on marital status, there was no significant difference in HIV-1 Ab distribution for the various age groups using modified Chi-square, G2 = 18.08 at [symbol: see text] = 0.01.HIV infection in Nigeria has not yet been manifested in major clinical terms, but the steady rate of increase in some African countries gives cause for concern. The authors assessed the prevalence of HIV-1 infection among 2206 male and female blood donors in Benin City, Nigeria. Benin City is located between HIV-1 and HIV-2 endemic zones, and is one of the five largest cities in Nigeria. Positive ELISA HIV-antibody test results were obtained for 19 donors, a seroprevalence of 0.9%; 11/1807 (0.6%) of the males and 8/399 (3.3%) of the females. The relative rate of infection between females and males was 3.29 with 95% confidence intervals of 1.33-8.14 by Fisher's Exact test. 9/239 (3.77%) of individuals aged 20-29 were HIV-seropositive, the highest prevalence of HIV infection among the age groups. Otherwise, the age groups 10-19 years, 30-39, 40-49, and 50 and over were infected as follows: 3/192 (1.56%), 4/725 (0.55%), 2/671 (0.3%), and 1/179 (0.26%), respectively. The marital status of the population studied made no difference with regard to the distribution of antibody to HIV.
Databáze: OpenAIRE