The Neuropeptide Y System Regulates Both Mechanical and Histaminergic Itch

Autor: Tianle, Gao, Haisha, Ma, Bo, Xu, Jessica, Bergman, Dan, Larhammar, Malin Charlotta, Lagerström
Rok vydání: 2018
Předmět:
Zdroj: The Journal of investigative dermatology. 138(11)
ISSN: 1523-1747
Popis: Itch is a somatosensory modality that serves to alert an organism to harmful elements removable by scratching, such as parasites and chemical irritants. Recently, ablation or silencing of neuropeptide Y (NPY)-expressing spinal interneurons was reported to selectively enhance mechanical itch, whereas chemical itch was unaffected. We examined the effect of activating the NPY/Y
Databáze: OpenAIRE