Characterization of the physicochemical interactions between exenatide and two intestinal permeation enhancers: Sodium caprate (C

Autor:	Caroline, Twarog, Elias, Fattal, Magali, Noiray, Brigitte, Illel, David J, Brayden, Myriam, Taverna, Hervé, Hillaireau
Rok vydání:	2022
Předmět:	Bile Acids and Salts Intestinal Absorption Glucagon-Like Peptide 1 Exenatide Water Caprylates Peptides Decanoic Acids Micelles
Zdroj:	International journal of pharmaceutics. 626
ISSN:	1873-3476
Popis:	A common approach to tackle the poor intestinal membrane permeability of peptides after oral administration is to formulate them with a permeation enhancer (PE). Increased oral bioavailability for oral peptide candidates has been reported from clinical trials when either salcaprozate sodium (SNAC) or sodium caprate (C
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::edf43da5833c5cee4995e94b8762f500 https://pubmed.ncbi.nlm.nih.gov/36028084 Zobrazit plný text záznamu Full Text from ScienceDirect