| Autor: |
Jonathan S, Abrahams, Michael R, Weigand, Natalie, Ring, Iain, MacArthur, Joss, Etty, Scott, Peng, Margaret M, Williams, Barret, Bready, Anthony P, Catalano, Jennifer R, Davis, Michael D, Kaiser, John S, Oliver, Jay M, Sage, Stefan, Bagby, M Lucia, Tondella, Andrew R, Gorringe, Andrew, Preston |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Microbial genomics. 8(2) |
| ISSN: |
2057-5858 |
| Popis: |
Bacterial genetic diversity is often described solely using base-pair changes despite a wide variety of other mutation types likely being major contributors. Tandem duplication/amplifications are thought to be widespread among bacteria but due to their often-intractable size and instability, comprehensive studies of these mutations are rare. We define a methodology to investigate amplifications in bacterial genomes based on read depth of genome sequence data as a proxy for copy number. We demonstrate the approach with |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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