| Autor: |
A, Tompa, G, Curtis, W, Ryan, C, Kuszynski, R, Langenbach |
| Rok vydání: |
1979 |
| Předmět: |
|
| Zdroj: |
Cancer letters. 7(2-3) |
| ISSN: |
0304-3835 |
| Popis: |
An antibody to benzo[alpha]pyrene (BP) was prepared. The isolated antibody showed a specificity for BP and a low reactivity with another carcinogenic hydrocarbon, 7,12-dimethylbenz[alpha]anthracene (DMBA). The BP-antibody inhibited the in vitro cytotoxic and mutagenic activity of BP in both a rat embryo fibroblast- and a rat lung cell-mediated mutagenesis system. A possible correlation of these in vitro findings to the in vivo carcinogenesis situation is discussed. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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