Silica coating of the pore walls of a microporous polycaprolactone membrane to be used in bone tissue engineering

Autor:	B, Demirdögen, C E Plazas, Bonilla, S, Trujillo, J E, Perilla, A E, Elcin, Y M, Elcin, J L Gómez, Ribelles
Rok vydání:	2013
Předmět:	Osteoblasts Coated Materials Biocompatible Tissue Engineering Osteogenesis Polyesters Animals Membranes Artificial Mesenchymal Stem Cells Silicon Dioxide Porosity Cells Cultured Rats
Zdroj:	Journal of biomedical materials research. Part A. 102(9)
ISSN:	1552-4965
Popis:	Polycaprolactone/silica microporous hybrid membranes were produced in two steps: A microporous polycaprolactone membrane with an interconnected porosity of 80% was obtained via a freeze extraction procedure, then silica was formed by a sol-gel reaction inside the micropores using tetraethyl orthosilicate, TEOS, as silica precursor. It is shown that silica forms a thin coating layer homogeneously distributed over the pore walls when sol-gel reaction is catalyzed by hydrochloric acid, while it forms submicron spherical particles when using basic catalyzer. Some physical properties and the viability and osteoblastic differentiation of bone marrow rat mesenchymal stem cells cultured on pure and hybrid membranes were studied.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::ecf4a90afae415936db4fb88cd1814a4 https://pubmed.ncbi.nlm.nih.gov/24167153 Zobrazit plný text záznamu Plný text