[Comparative choleretic properties of natural xanthone compounds from Gentianopsis barbata]

Autor: S M, Nikolaev, Z G, Sambueva, A V, Tsyrenzhapov, G G, Nikolaeva, L M, Tankhaeva, V I, Glyzin, T D, Dargaeva
Rok vydání: 2003
Předmět:
Zdroj: Eksperimental'naia i klinicheskaia farmakologiia. 66(4)
ISSN: 0869-2092
Popis: Comparative data are presented for the choleretic activity of xanthones isolated from Gentianopsis barbata (Froel.) Ma. (Gentianaceae family): a sum of xanthone glycosides (I) and aglycons (II); xanthone aglycons, including decussatin [1-(OH)-3,7,8-(OCH3)3] (III) and gentiacaulein [1,7-(OH)-3,8-(OCH3)2] (IV); and xanthone glycoside gentiabavaroside [1-O-primverosyl-7-(OH)-3,8-(OCH3)2] (V). It was established that (II) is superior to (I) with respect to cholagogic effect and is inferior to (III) and (IV) with respect to cholatostimulant action.
Databáze: OpenAIRE