[Antimutagenic properties of substances containing beta-carotene]

Autor: M A, Shliankevich, O B, Drize, V M, Khabibulina, A V, Sergeev, E G, Privalova, V G, Nikitiuk
Rok vydání: 1992
Předmět:
Zdroj: Voprosy meditsinskoi khimii. 38(6)
ISSN: 0042-8809
Popis: Two carotene-containing drugs (natural and artificial) were shown to decrease the rate of chromosomal aberrations, induced by cyclophosphane, in bone marrow cells of mice, daily ration of which contained 10-20 mg/kg of beta-carotene within 1-3 weeks. The rate of chromosomal aberrations induced was decreased 1.5-2-fold in various experiments. Artificial beta-carotene exhibited aftereffect within at least 3 days, while its protective effect was decreased about by 20% within 7 days after administration.
Databáze: OpenAIRE