Human and porcine neurocysticercosis: differences in the distribution and developmental stages of cysticerci

Autor:	B, Sáenz, J, Ramírez, A, Aluja, A, Escobar, G, Fragoso, J, Morales, R, Pérez-Tamayo, F, Rosetti, C, Larralde, E, Sciutto, A, Fleury
Rok vydání:	2008
Předmět:	Swine Diseases Brain Diseases Swine Taenia solium Animals Brain Humans Cysticercus Neurocysticercosis Magnetic Resonance Imaging
Zdroj:	Tropical medicineinternational health : TMIH. 13(5)
ISSN:	1365-3156
Popis:	To describe and compare the clinical impacts of neurocysticercosis (NC) caused by Taenia solium in humans and pigs.Comparative study of the brains of 16 asymptomatic pigs and 35 human NC cases (15 asymptomatic and 20 symptomatic).In humans, cysticerci were more frequently located in the ventricles and subarachnoid space at the base of the brain (11.8%vs. 1.6%; P = 0.001 and 25.9%vs. 0%; P0.0001, respectively) while in pigs, cysticerci were more frequently found in the parenchyma (44.4%vs. 7.6%; P0.0001). In human brains, 75.9% of the cysticerci were calcified, while in pigs all cysticerci were in the vesicular stage.The duration of infection and the host-parasite relationship (such as immune reactivity and brain haemodynamics) differ between humans and pigs. This may account for the different distribution and stage of the cysticerci among humans and pigs.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::ecd0ba570c9f3457c3c7c6d3d73f2bfe https://pubmed.ncbi.nlm.nih.gov/18384482 Zobrazit plný text záznamu Plný text