| Autor: |
Carolina, Scagnolari, Fabio, Midulla, Simona, Trombetti, Alessandra, Pierangeli, Valeria, Tromba, Rosanna, Grossi, Paola, Di Marco, Caterina, Dianzani, Enrico, Girardi, Guido, Antonelli |
| Rok vydání: |
2007 |
| Předmět: |
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| Zdroj: |
Experimental biology and medicine (Maywood, N.J.). 232(10) |
| ISSN: |
1535-3702 |
| Popis: |
To determine whether there is an airway IFN response in infants with acute bronchiolitis and to establish whether the rate of such a response is related to the severity of illness, the expression of some IFN-induced genes was measured in nasopharyngeal washes from 39 infants with acute bronchiolitis. The results indicate that in infants with a virus-associated acute bronchiolitis there is a strong activation of IFN system and that the severity of illness is inversely related to the level of expression of IFN-induced genes. This suggests that the IFN response plays an important role in determining virus-associated respiratory disease in early life. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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