| Autor: |
F E, Hull, J F, Radloff, C C, Sweeley |
| Rok vydání: |
1975 |
| Předmět: |
|
| Zdroj: |
Recent advances in studies on cardiac structure and metabolism. 8 |
| ISSN: |
0363-5872 |
| Popis: |
Ischemia markedly depresses fatty acid oxidation and increases fatty acyl-CoA and fatty acylcarnitine levels in the isolated heart during palmitate oxidation. Evidence suggests that the major defect is impaired beta-oxidation due to decreased electron transport rather than to diminished fatty acyl uptake, activation, or intramitochondrial transfer. Important metabolic effects may include decreased mitochondrial adenine nucleotide translocation and altered carnitine-palmity-l-CoA transferase activity. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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