| Autor: |
Nagaraju, Tumula, Nagesh, Jatangi, Radha Krishna, Palakodety, Sridhar, Balasubramanian, Mangarao, Nakka |
| Rok vydání: |
2017 |
| Zdroj: |
The Journal of organic chemistry. 82(10) |
| ISSN: |
1520-6904 |
| Popis: |
A novel and expeditious approach for the synthesis of N-fused and 3,4-disubstituted 5-imino-1,2,4-thiadiazole derivatives has been achieved through the molecular iodine-catalyzed oxidative cyclization of 2-aminopyridine/amidine and isothiocyanate via N-S bond formation at ambient temperature. The present one-pot transition-metal-free protocol provides the facile and highly efficient regiospecific synthesis of various 1,2,4-thiadiazole derivatives in a scaled-up manner with good to excellent yields using inexpensive I |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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