Stimulation of rat pituitary tumoral cell proliferation in vitro by tetra- and pentagastrin

Autor: M, Pawlikowski, J, Kunert-Radek, K D, Döhler
Rok vydání: 1992
Předmět:
Zdroj: Endokrynologia Polska. 43(4)
ISSN: 0423-104X
Popis: The effects of the active gastrin fragments, penta- and tetragastrin on the incorporation of tritiated thymidine into the rat pituitary tumoral cells were investigated in vitro. The significant stimulation of 3H-thymidine incorporation was observed as an effect of the investigated substances. The putative role of gastrin as an autocrine growth factor active in pituitary tumorigenesis was discussed.
Databáze: OpenAIRE