[Chronic migraine: pathophysiology]
Autor: | Margarita, Sánchez del Río-González |
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Rok vydání: | 2012 |
Předmět: |
Inflammation
Fibromyalgia Sympathetic Nervous System Mood Disorders Migraine Disorders Peptide Hormones Brain Foramen Ovale Patent Neuroimaging Pain Perception Comorbidity Irritable Bowel Syndrome Sleep Apnea Syndromes Intracranial Embolism Hyperalgesia Risk Factors Chronic Disease Headache Disorders Secondary Prevalence Humans Obesity Trigeminal Nerve |
Zdroj: | Revista de neurologia. 54 |
ISSN: | 1576-6578 |
Popis: | Chronic migraine is considered a complication of episodic migraine. Several risk factors, which may be modifiable or non-modifiable, make varying contributions to the progression towards chronification. Every year 2.5% of patients with episodic migraine go on to suffer chronic migraine. Experimental studies point to a dysfunction in the descending pain modulatory system that would facilitate nociceptive afferents, in the absence of damage to tissues, and so chronic migraine would share a pathogenesis that is similar to that of fibromyalgia, irritable bowel syndrome or chronic tension-type headache (conditions that frequently coexist). This paper reviews the risk factors and the scientific evidence of the possible pathogenic mechanisms involved in the progression towards chronification. |
Databáze: | OpenAIRE |
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