FAP

Autor: Luyao, Sun, Miaola, Ke, Xin, Wang, Mengyuan, Yin, Junni, Wei, Lu, Xu, Xing, Tian, Fei, Wang, He, Zhang, Songbin, Fu, Chunyu, Zhang
Rok vydání: 2022
Předmět:
Zdroj: Molecular carcinogenesis. 61(10)
ISSN: 1098-2744
Popis: Ovarian cancer is the most lethal gynecological malignancy worldwide with high metastasis and poor prognosis rates. Cancer-associated fibroblasts (CAFs), a heterogeneous population of cells that constitutes a major component of the tumor microenvironment, secrete extracellular vesicles (EVs) loading with proteins, lipids, and RNAs to promote tumorigenesis. However, the specific roles of CAF-derived proteins contained in EVs in ovarian cancer remain poorly understood at present. Using the gene expression microarray analysis, we identified a list of dysregulated genes between the α-SMA
Databáze: OpenAIRE