| Autor: |
Z, Zhang, Y, Batres, S Y, Ying |
| Rok vydání: |
1996 |
| Předmět: |
|
| Zdroj: |
Anticancer research. 16(1) |
| ISSN: |
0250-7005 |
| Popis: |
Activin regulates the growth and differentiation of a variety of cells and is a member of the transforming growth factor-beta (TGF-beta) family. Previously, we found that the retinoblastoma cell line Y-79 expresses both activins and activin receptors, suggesting that activin may have an autocrine function in these cells. In this study, the effects of exogeneous activin A on cultured Y-79 cells were examined. The results demonstrate that activin A inhibits hexamethylene bisacetamide (HMBA) -induced Y-79 cell differentiation in both serum-containing and serum-free medium. Activin A also inhibits Y-79 cell growth in serum-containing medium but not in serum-free medium. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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