Rarity of surgical complications after postchemotherapy nephrectomy for nephroblastoma. Experience of the International Society of Paediatric Oncology-Trial and Study 'SIOP-9'. International Society of Paediatric Oncology Nephroblastoma Trial and Study Committee

Autor: J, Godzinski, M F, Tournade, J, deKraker, J, Lemerle, P A, Voute, A, Weirich, R, Ludwig, M, Rapala, G, Skotnicka, F, Gauthier, C G, Moorman-Voestermans, D, Buerger, A, VanVeen, K, Sawicz-Birkowska
Rok vydání: 1998
Předmět:
Zdroj: European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie. 8(2)
ISSN: 0939-7248
Popis: The aim of the study was to assess rates and types of nephrectomy-related complications in children nephrectomized for nephroblastoma after preoperative chemotherapy. Records of 598 Wilms' tumour patients registered in the International Society of Paediatric Oncology TrialStudy No. 9 (SIOP-9), and pretreated correctly according to the protocol with vincristine + actinomycin D +/- epirubicine or adriamycin prior to nephrectomy, were retrospectively reviewed. Forty-nine patients (8%), who suffered from 54 complications, were identified. Most frequent events were small-bowel occlusions (3.7%) and tumour ruptures (2.8%). Other complications were registered in 2.0% of cases. The low rate of nephrectomy complications and no deaths related to registered ones, are another argument for preoperative chemotherapy in Wilms' tumour patients.
Databáze: OpenAIRE