Unraveling the mechanism for respiratory rhythm generation

Autor: D R, McCrimmon, J M, Ramirez, S, Alford, E J, Zuperku
Rok vydání: 2000
Předmět:
Zdroj: BioEssays : news and reviews in molecular, cellular and developmental biology. 22(1)
ISSN: 0265-9247
Popis: Breathing is generated by a neuronal network located within the caudal brainstem. One area of particular significance for respiratory rhythm generation is the pre-Bötzinger (preBotC) complex in the ventrolateral medulla. An important step towards understanding the cellular and network basis by which neurons within this region generate the respiratory rhythm was made in a recent study by Koshiya and Smith.(1) Using simultaneous image analysis and electrophysiological techniques these authors identified a discrete population of synaptically-coupled pacemaker neurons within the preBotC. They postulated that these neurons constitute the minimal essential network component (kernel) for generating the respiratory rhythm. BioEssays 22:6-9, 2000.
Databáze: OpenAIRE