| Autor: |
V S, Ter-Griggorov, O Ia, Moskovkina, V E, Krupnik, I A, Graf, A V, Pivnik |
| Rok vydání: |
1988 |
| Předmět: |
|
| Zdroj: |
Eksperimental'naia onkologiia. 10(6) |
| ISSN: |
0204-3564 |
| Popis: |
Antibodies exhibiting a selective anti-H-2 haplotype reaction with thymic and splenic lymphocytes of intact mice were found in the sera of mice of the strains BALB/c, C57Bl/6, AKR and BDF1 with the developing Rauscher leukemia by applying the membrane immunofluorescent and complement-dependent cytotoxicity techniques in vitro. Monoclonal antibodies against H-2 IAd and H-2 IAk and sorption tests using lymphocytes of the congenic-resistant strains as target cells were used to show that the aforementioned antibodies acted against autoantigens which are the products of the genes of the I-subregion of the H-2 histocompatibility complex. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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